
隨著人們?nèi)找骊P(guān)注腸道健康如何影響心理健康,,研究人員發(fā)現(xiàn)益生菌或?qū)⒊蔀閷?duì)抗負(fù)面情緒的新一代突破性膳食補(bǔ)充劑,。
《npj心理健康研究》(npj Mental Health Research)期刊近期發(fā)布的一項(xiàng)最新小型研究表明,,健康成年人每日服用益生菌補(bǔ)充劑與焦慮、壓力和疲勞感顯著降低存在相關(guān)性,。這項(xiàng)隨機(jī),、雙盲、安慰劑對(duì)照實(shí)驗(yàn)對(duì)88名健康志愿者進(jìn)行了每日情緒追蹤,,發(fā)現(xiàn)受試者在服用益生菌兩周后情緒有所改善。
益生菌是腸道中的"有益"菌群,,存在于酸奶,、泡菜、開(kāi)菲爾和康普茶等發(fā)酵食品中,。近期,,美國(guó)醫(yī)療補(bǔ)助與醫(yī)療保險(xiǎn)負(fù)責(zé)人穆罕默德·奧茲博士剛剛推薦益生菌。腸道內(nèi)存在著由數(shù)萬(wàn)億微生物(包括細(xì)菌,、病毒和真菌)組成的腸道微生物群,。為維持腸道健康,,這些菌群需要得到滋養(yǎng)和保護(hù)——這正是富含益生菌的食物和補(bǔ)充劑的作用所在。
在該研究中,,參與者被分為兩組:一組在28天內(nèi)服用含九種菌株的益生菌,,另一組服用安慰劑。隨后受試者需完成心理問(wèn)卷,、每日情緒報(bào)告,,并通過(guò)計(jì)算機(jī)任務(wù)測(cè)試情緒處理能力。
兩周后,,研究人員觀察到益生菌組的負(fù)面情緒顯著減少,,但積極情緒未受影響。
研究的作者之一勞拉·斯滕貝亨表示:“令人驚訝的是,,僅通過(guò)每日詢問(wèn)受試者的感受,,我們就能檢測(cè)到益生菌對(duì)情緒的有益影響?!?
腸腦連接
越來(lái)越多證據(jù)表明腸道健康影響心理健康,。
研究的作者之一卡特琳娜·約翰遜表示:“腸腦連接通過(guò)多種途徑讓腸道細(xì)菌影響我們的感受和行為,包括迷走神經(jīng),、免疫系統(tǒng)和激素等通路,。”這意味著腸道與大腦直接溝通,,左右著我們的心理健康,。
研究顯示,腸道炎癥也會(huì)導(dǎo)致情緒紊亂,,包括與焦慮相關(guān)的心理健康問(wèn)題,。
在這項(xiàng)最新研究中,研究人員發(fā)現(xiàn)益生菌組不僅整體負(fù)面情緒減少,,焦慮,、壓力、擔(dān)憂和反復(fù)思慮等具體感受也有所降低,。研究人員還注意到,,益生菌對(duì)情緒改善效果最顯著的是那些自稱“風(fēng)險(xiǎn)規(guī)避型”的受試者。
斯滕貝亨表示:“或許未來(lái)益生菌可作為早期干預(yù)靶向手段,,防止負(fù)面情緒發(fā)展為抑郁癥等心理健康問(wèn)題,,但這方面需要更多研究驗(yàn)證?!?/p>
益生菌的三大潛在益處
盡管并非所有人都認(rèn)同益生菌的益處,,這種被超過(guò)1,000項(xiàng)臨床試驗(yàn)研究的補(bǔ)充劑除了改善情緒,還可能通過(guò)多種方式促進(jìn)健康,。根據(jù)美國(guó)國(guó)立衛(wèi)生研究院(National Institutes of Health ,,NIH)膳食補(bǔ)充劑辦公室的研究,,大量研究證明益生菌的益處包括:
1. 緩解腸胃問(wèn)題
益生菌可降低抗生素相關(guān)的腹瀉風(fēng)險(xiǎn)(這種腹瀉源于抗生素破壞腸道菌群),在患者首次服用抗生素兩天內(nèi)開(kāi)始補(bǔ)充益生菌時(shí)效果尤其顯著,。NIH還指出,,有部分證據(jù)表明單菌株/多菌株益生菌能緩解兒童急性感染性腹瀉的癥狀和病程。
炎癥性腸?。↖BD)包括潰瘍性結(jié)腸炎和克羅恩病等慢性炎癥疾病,。雖無(wú)法根治,但研究表明益生菌有助控制癥狀,,不過(guò)NIH強(qiáng)調(diào)臨床指南尚未明確推薦將其用于治療炎癥性腸病,。
腸易激綜合征(IBS)癥狀與IBD類似且會(huì)引發(fā)消化系統(tǒng)紊亂,但不被認(rèn)定為一種疾病,,且不會(huì)導(dǎo)致腸道炎癥或損傷,。但其癥狀可能只是造成紊亂,NIH表示特定益生菌產(chǎn)品可能恢復(fù)部分微生物群功能,,幫助控制其癥狀,。
2. 降低膽固醇
研究表明某些益生菌組合可改善血脂指標(biāo),特別是降低總膽固醇和低密度膽固醇(“壞”膽固醇),。但需更多研究明確益生菌與膽固醇之間的關(guān)聯(lián),。
3. 輔助體重和肥胖管理
由于腸道微生物幫助從食物中提取營(yíng)養(yǎng)和能量(從而影響熱量消耗與儲(chǔ)存),NIH指出益生菌或能成為體重管理工具,。部分關(guān)于益生菌與肥胖癥的臨床試驗(yàn)已顯示出積極結(jié)果,,但尚需深入驗(yàn)證。 (財(cái)富中文網(wǎng))
譯者:劉進(jìn)龍
審校:汪皓
隨著人們?nèi)找骊P(guān)注腸道健康如何影響心理健康,,研究人員發(fā)現(xiàn)益生菌或?qū)⒊蔀閷?duì)抗負(fù)面情緒的新一代突破性膳食補(bǔ)充劑,。
《npj心理健康研究》(npj Mental Health Research)期刊近期發(fā)布的一項(xiàng)最新小型研究表明,健康成年人每日服用益生菌補(bǔ)充劑與焦慮,、壓力和疲勞感顯著降低存在相關(guān)性,。這項(xiàng)隨機(jī)、雙盲,、安慰劑對(duì)照實(shí)驗(yàn)對(duì)88名健康志愿者進(jìn)行了每日情緒追蹤,,發(fā)現(xiàn)受試者在服用益生菌兩周后情緒有所改善。
益生菌是腸道中的"有益"菌群,,存在于酸奶,、泡菜、開(kāi)菲爾和康普茶等發(fā)酵食品中,。近期,美國(guó)醫(yī)療補(bǔ)助與醫(yī)療保險(xiǎn)負(fù)責(zé)人穆罕默德·奧茲博士剛剛推薦益生菌,。腸道內(nèi)存在著由數(shù)萬(wàn)億微生物(包括細(xì)菌,、病毒和真菌)組成的腸道微生物群,。為維持腸道健康,這些菌群需要得到滋養(yǎng)和保護(hù)——這正是富含益生菌的食物和補(bǔ)充劑的作用所在,。
在該研究中,,參與者被分為兩組:一組在28天內(nèi)服用含九種菌株的益生菌,另一組服用安慰劑,。隨后受試者需完成心理問(wèn)卷,、每日情緒報(bào)告,并通過(guò)計(jì)算機(jī)任務(wù)測(cè)試情緒處理能力,。
兩周后,,研究人員觀察到益生菌組的負(fù)面情緒顯著減少,但積極情緒未受影響,。
研究的作者之一勞拉·斯滕貝亨表示:“令人驚訝的是,,僅通過(guò)每日詢問(wèn)受試者的感受,我們就能檢測(cè)到益生菌對(duì)情緒的有益影響,?!?
腸腦連接
越來(lái)越多證據(jù)表明腸道健康影響心理健康。
研究的作者之一卡特琳娜·約翰遜表示:“腸腦連接通過(guò)多種途徑讓腸道細(xì)菌影響我們的感受和行為,,包括迷走神經(jīng),、免疫系統(tǒng)和激素等通路?!边@意味著腸道與大腦直接溝通,,左右著我們的心理健康。
研究顯示,,腸道炎癥也會(huì)導(dǎo)致情緒紊亂,,包括與焦慮相關(guān)的心理健康問(wèn)題。
在這項(xiàng)最新研究中,,研究人員發(fā)現(xiàn)益生菌組不僅整體負(fù)面情緒減少,,焦慮、壓力,、擔(dān)憂和反復(fù)思慮等具體感受也有所降低,。研究人員還注意到,益生菌對(duì)情緒改善效果最顯著的是那些自稱“風(fēng)險(xiǎn)規(guī)避型”的受試者,。
斯滕貝亨表示:“或許未來(lái)益生菌可作為早期干預(yù)靶向手段,,防止負(fù)面情緒發(fā)展為抑郁癥等心理健康問(wèn)題,但這方面需要更多研究驗(yàn)證,?!?/p>
益生菌的三大潛在益處
盡管并非所有人都認(rèn)同益生菌的益處,這種被超過(guò)1,000項(xiàng)臨床試驗(yàn)研究的補(bǔ)充劑除了改善情緒,還可能通過(guò)多種方式促進(jìn)健康,。根據(jù)美國(guó)國(guó)立衛(wèi)生研究院(National Institutes of Health ,,NIH)膳食補(bǔ)充劑辦公室的研究,大量研究證明益生菌的益處包括:
1. 緩解腸胃問(wèn)題
益生菌可降低抗生素相關(guān)的腹瀉風(fēng)險(xiǎn)(這種腹瀉源于抗生素破壞腸道菌群),,在患者首次服用抗生素兩天內(nèi)開(kāi)始補(bǔ)充益生菌時(shí)效果尤其顯著,。NIH還指出,有部分證據(jù)表明單菌株/多菌株益生菌能緩解兒童急性感染性腹瀉的癥狀和病程,。
炎癥性腸?。↖BD)包括潰瘍性結(jié)腸炎和克羅恩病等慢性炎癥疾病。雖無(wú)法根治,,但研究表明益生菌有助控制癥狀,,不過(guò)NIH強(qiáng)調(diào)臨床指南尚未明確推薦將其用于治療炎癥性腸病。
腸易激綜合征(IBS)癥狀與IBD類似且會(huì)引發(fā)消化系統(tǒng)紊亂,,但不被認(rèn)定為一種疾病,,且不會(huì)導(dǎo)致腸道炎癥或損傷。但其癥狀可能只是造成紊亂,,NIH表示特定益生菌產(chǎn)品可能恢復(fù)部分微生物群功能,,幫助控制其癥狀。
2. 降低膽固醇
研究表明某些益生菌組合可改善血脂指標(biāo),,特別是降低總膽固醇和低密度膽固醇(“壞”膽固醇),。但需更多研究明確益生菌與膽固醇之間的關(guān)聯(lián)。
3. 輔助體重和肥胖管理
由于腸道微生物幫助從食物中提取營(yíng)養(yǎng)和能量(從而影響熱量消耗與儲(chǔ)存),,NIH指出益生菌或能成為體重管理工具,。部分關(guān)于益生菌與肥胖癥的臨床試驗(yàn)已顯示出積極結(jié)果,但尚需深入驗(yàn)證,。 (財(cái)富中文網(wǎng))
譯者:劉進(jìn)龍
審校:汪皓
As interest grows around how gut health might impact mental health, researchers have discovered that probiotics could be the next breakthrough supplement to fight negative emotions.
A small new study published in the journal npj Mental Health Research found that daily probiotic supplements were associated with significantly reduced anxiety, stress, and fatigue in healthy adults. The randomized, double-blind, placebo-controlled design in 88 healthy volunteers reported their mood daily, and saw improved mood after two weeks of taking probiotics.
Probiotics—endorsed by recently confirmed Medicaid and Medicare head Dr. Mehmet Oz—are the “good” bacteria in your gut, found in fermented foods like yogurt, kimchi, kefir, and kombucha. Within your gut lies the gut microbiome, made up of trillions of microorganisms including bacteria, viruses, and fungi. To keep your gut healthy, that bacteria needs to be fed and maintained—which is where probiotic-rich foods and supplements can help.
For the study, participants were split into two groups, with one group taking a probiotic containing nine bacterial strains over the course of 28 days and the other given a placebo. Subjects then completed psychological questionnaires, a daily mood report, and computer tasks testing how they were processing their emotions.
Once they hit the two-week mark, researchers observed that the probiotic group’s negative mood significantly reduced, while there was no impact on positive mood.
“It is striking that by simply asking participants how they were feeling each day, we could detect the beneficial effects of probiotics on mood,” said study co-author Laura Steenbergen.
The gut-brain connection
There is mounting evidence that your gut health impacts your mental health.
“The gut-brain connection provides various routes through which bacteria in the gut can influence how we feel and behave, including via the vagus nerve, immune system and hormones,” said study co-author Katerina Johnson. That means that our gut directly communicates with our brain, impacting our mental wellbeing.
Inflammation in your gut can also lead to mood disruption, studies show, including anxiety-related mental health issues.
In this new study, researchers found that the group taking probiotics had not only an overall reduction in negative emotions, but lower feelings of anxiety, stress, worry, and rumination. Researchers also noted that those who had the greatest effect from the probiotics on their mood were those who self-described as risk-avoidant.
“Perhaps in the future probiotics could be used in a targeted way as an early intervention to reduce the chances of negative feelings progressing to mental health conditions such as depression, though more research would be needed to confirm that,” says Steenbergen.
3 more potential benefits of probiotics
While not everyone agrees that probiotics have benefits, they are a heavily studied supplement—with over 1,000 clinical trials and counting—that could potentially support your health in myriad ways in addition to mood. According to the National Institutes of Health (NIH) Office of Dietary Supplements, well-researched benefits of probiotics may include:
1. Easing stomach issues
Probiotics have been shown to reduce the risk of antibiotic-associated diarrhea, which can happen as a result of antibiotics disrupting the gut microbiome, specifically when patients started taking probiotics within two days of the first antibiotic dose. The NIH also points out that some evidence links single- and multi-strain probiotics to alleviating the symptoms and duration of acute infectious diarrhea in children.
Inflammatory bowel disease (IBD) is a chronic inflammatory disease that includes ulcerative colitis and Crohn’s disease. While there is no cure for it, research reflects that probiotics can help manage symptoms, although the NIH notes that clinical guidelines do not specifically recommend probiotics for IBD.
Irritable bowel syndrome (IBS), which presents similarly to IBD and causes disruption to the digestive system, is not considered a disease and does not lead to inflamed or damaged intestines. However, its symptoms can be just as disruptive—and according to the NIH, certain probiotic products have the potential to restore some microbiome functionality and help manage the symptoms of this condition.
2. Lowering cholesterol
Taking combinations of certain probiotic strains could help improve lipid profiles, research indicates—specifically reducing total and LDL (bad) cholesterol. However, more research is still needed to understand the full extent of probiotics and cholesterol.
3. Supporting weight management and obesity
Since the microbes of the intestinal tract help extract nutrients and energy from food—therefore impacting calorie expenditure and storage—the NIH reports that probiotics could be a tool used in weight management. Some clinical trials on probiotics and obesity have reported potentially positive results, but more research is still needed.